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Contemporary Topics in Immunobiology: Thymus Dependency by A. J. S. Davies, R. L. Carter (auth.), A. J. S. Davies, R.

By A. J. S. Davies, R. L. Carter (auth.), A. J. S. Davies, R. L. Carter (eds.)

This moment quantity of up to date issues in Immunobiology considers many points of thymus dependency as a way to exemplify the position of the thy­ mus in numerous species and diverse immunological responses. it isn't in­ tended to be a compendium of the responses that have been proven to be thymus based yet fairly to demonstrate for the reader the factors he may still follow in puzzling over the importance of the thymus in immune responses. we're thankful to the editors and publishers of the Annals of the hot York Academy of technological know-how, the Australian magazine of Experimental Biology and scientific technology, scientific and Experimental Immunology, Immunology, the magazine of Experimental drugs, the magazine of Immunology, Laboratory research, Nature, and the court cases of the Royal Society of drugs and to Springer-Verlag, Berlin, for permission to breed illustrations. particular references are given within the textual content. we might additionally wish to thank the members for his or her time and effort and willingness to undergo the editorial pink pencils. The workout of those censori­ ous tools intended that the manuscripts needed to be reorganized and retyped. Mrs. J. Pettis, Mrs. A. Inglefield, and leave out M. Butt all helped, and we're such a lot thankful to them. A.J.S.D. R.L.e.

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J. Anat. 22:127. Wallin, I. , 1918. Anat. Rec. 14:205. Webster, W. , 1934. J. Morpho/, 56:295. , 1965. Zellforsch. Mikroscop. Anat. Abt. Histochem. 65:256. liIn general, thymectomy carried out in adult life causes little subsequent alteration in immunological reactivity; thymectomy performed in small laboratory rodents shortly after birth often produces striking deficiencies, particularly in cell-mediated immune responses such as homograft rejection and delayed-type hypersensitivity reactions. Some strains of mice when thymectomized at birth become more susceptible to infections and undergo a runting syndrome which leads to their premature death; they also have defective humoral antibody responses to certain antigens (Miller, 1961; Parrott, 1962; Miller and Osoba, 1967).

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